Cyclin D1 encodes the regulatory subunit of a holoenzyme that phosphorylates and inactivates the retinoblastoma protein and promotes progression through the G1-S phase of the cell cycle. 周期素D1编码一种全酶的调节亚单位,该酶利用蛋白磷酸化灭活视网膜母细胞瘤蛋白,通过细胞周期G1-S期促进肿瘤进展恶化。
Expression, Purification and Characterization of Regulatory Subunit of Type I cAMP dependent Protein Kinase in E. coli 重组I型cAMP依赖的蛋白激酶调节亚基的表达、纯化和鉴定
Characterization of Transcriptional Regulatory Elements Within First Intron of the A Subunit Gene of Coagulation Factor ⅷ 凝血因子FⅧA链基因第1内含子内顺式调节元件的鉴定
Cyclin D3 is found to play a crucial role not only in progression through the G1 phase as a regulatory subunit of CDK 4 and CDK 6, but also in many other aspects, such as cell growth, cell differentiation, transcriptional regulation and apoptosis. 在cyClinD中,cyClinD3不仅作为一个CDK4和CDK6的调节亚基在G1期调节细胞周期进程,还与细胞生长、细胞分化、转录调节和凋亡有关。
Study on the regulatory effects of hepatitis C virus on the expression of nascent polypeptide-associated complex α subunit gene 丙型肝炎病毒对新生多肽相关复合物α多肽基因的表达调节研究进展
The biosensor chip was eluted to collect the stripped proteins for MALDI-TOF MS. After searching database, one protein interacting with SARS-CoV NP was identified, which is 26S protease regulatory subunit S10B ( Proteasome subunit p42)( Proteasome 26S subunit ATPase 6)( P62333). 结果鉴定出与SARS-CoV核蛋白相互作用的蛋白:26S蛋白酶调节亚单位S10B(蛋白酶体亚单位p42)(蛋白酶体26S亚单位ATPase6)(P62333),属于泛素/蛋白酶体系统;
It might encode a germ cell-specific proteasome regulatory particle subunit and play a potential role in spermatogenesis and normal sperm physiology. 推测该基因编码生殖细胞特异的蛋白酶体调控元件的亚单位,可能与精子发生和精子生理功能潜在相关。
CAMP combines the regulatory subunit, releases the catalytic subunits and activates the PKA. cAMP和PKA的调节亚基结合,释放出其催化亚基而激活了PKA。